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HaXS8 Size:100nmol S)-AHPC-CO-C6-NH2 HCl Synonyms CAS Number

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Description

S)-AHPC-CO-C6-NH2 HCl Synonyms CAS Number 2360522-76-3 Related CAS 2306389-03-5 (free base)

Product Name DOTA-PEG2-C2-amine Synonyms CAS Number 2866181-83-9 Related CAS Molecular Formula C22H42N6O9 Molecular Weight 534

m-PEG4 is attached to the commonly used self-immolative para-aminobenzyl (PAB) moiety to further increase aqueous solubility

1038/s41586-019-1722-1

Datasheet          MSDS

HaXS8 Size:100nmol S)-AHPC-CO-C6-NH2 HCl Synonyms CAS NumberHaXS8 is a synthetic chemical dimerizer designed to induce covalent and irreversible intracellular dimerization between proteins tagged with HaloTag and SNAP tag. Its a bifunctional molecule featuring a chloroalkane group (specific for HaloTag) and an O6 benzylguanine (BG) derivative (specific for SNAP tag), connected by a flexible polyethylene glycol (PEG) linker. When introduced to cells, HaXS8 bridges HaloTag and SNAP tag fusion proteins by

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