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Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:5mg This activation process results in

SKU: 23583043376

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Description

This activation process results in a bright green fluorescence

Product Name Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C77H96FN11O23 Molecular Weight 1562

Product Name: 5(6)-ROX alkyne Synonyms: 5-(and 6)-Carboxy-X-rhodamine alkyne CAS Number: N/A Molecular Formula: C36H33N3O4 Molecular Weight: 571

73 Purity (HPLC) >= 95% Solubility DMSO

Product Name Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C93H155N13O31 Molecular Weight 1951

Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:5mg This activation process results inSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent

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