Mal-Propionyl-PEG8-Gly-Gly-Phe-Gly-PAB(m-PEG4) deuterium-labeled-amine Product Name Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Synonyms CAS

Product Name Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C85H112FN11O27 Molecular Weight 1738

VHL-SNAP2-5C is a SNAP PROteolysis TArgeting Chimera (SNAP-PROTAC)

S)-AHPC-acetamido-O-PEG5-C1-acid Synonyms CAS Number 2361117-11-3 Related CAS Molecular Formula C36H54N4O12S Molecular Weight 766

Product Name 1-[2-(piperazin-1-yl)ethyl]piperazine 4TFA Synonyms CAS Number Related CAS 19479-83-5 Molecular Formula C10H22N4 Molecular Weight 198

308 SMILES BrCCCCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-PEG8-Gly-Gly-Phe-Gly-PAB(m-PEG4) deuterium-labeled-amine Product Name Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker