Propargyl-Acetyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE deuterium-labeled-amine Product Name 6-FAM C2 maleimide

Product Name 6-FAM C2 maleimide Synonyms CAS Number N/A Related CAS Molecular Formula C27H18N2O8 Molecular Weight 498

Product Name Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C88H139N15O24 Molecular Weight 1791

originally isolated from Rhodococcus rhodochrous

Product Name 2-chloro-5-(methoxy-d3)pyrimidine Synonyms CAS Number n/a Related CAS Molecular Formula C5H5ClN2O Molecular Weight 147

Chloroquinaxoline sulfonamide (CQS) share the same mechanism of action as Indisulam

Propargyl-Acetyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE deuterium-labeled-amine Product Name 6-FAM C2 maleimideSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate