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DBCO-Propionyl-Val-Ala-PAB(m-PEG8)-MMAE Size:10mg 188 Purity (HPLC) >= 95%

SKU: 4646522720

4.3
USD445.00 USD482.00

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Description

188 Purity (HPLC) >= 95% Solubility DMSO

Hormone Receptor-Positive

Product Name Phthalimidinoglutarimide-5'-C7-OH Synonyms CAS Number n/a Related CAS Molecular Formula C20H26N2O4 Molecular Weight 358

009 Purity (HPLC) >= 95% Solubility DMSO

Product Name DOTA-tris(t-Bu)ester-PEG1-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C32H60N8O8 Molecular Weight 684

DBCO-Propionyl-Val-Ala-PAB(m-PEG8)-MMAE Size:10mg 188 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

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