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Product Name Phthalimidinoglutarimide-C3-O-PEG2-OH Synonyms Phthalimidinoglutarimide-4'-C3-O-PEG2-OH CAS Number n/a Related CAS Molecular Formula C20H26N2O6 Molecular Weight 390
Product Name Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C88H139N15O24 Molecular Weight 1791
Rational discovery of molecular glue degraders via scalable chemical profiling
Cy5-CA CAS Number Related CAS Molecular Formula C42H59ClN3O3 Molecular Weight 689
314 SMILES OC(=O)C(F)(F)F
Mal-Propionyl-PEG8-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan Size:10mg Product Name Phthalimidinoglutarimide-C3-O-PEG2-OH Synonyms Phthalimidinoglutarimide-4'-C3-O-PEG2-OHSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent
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